If you're not using black plastic, mulch the vines 2 weeks after planting to smother weeds, conserve moisture, and keep the soil loose for root development. Occasionally lift longer vines to keep them from rooting at the joints, or they will put their energy into forming many undersized tubers at each rooted area rather than ripening the main crop at the base of the plant. Otherwise, handle plants as little as possible to prevent wounds that might be invaded by disease spores.
If the weather is dry, provide 1 inch of water a week until 2 weeks before harvesting, then let the soil dry out a bit. Don't overwater, or the plants—which can withstand dry spells better than rainy ones—may rot.
Southern gardeners are more likely to encounter pest problems than gardeners in Northern areas.
Sweet potato weevils—1/4-inch-long insects with dark blue heads and wings and red-orange bodies—puncture stems and tubers to lay their eggs. Developing larvae tunnel and feed on the fleshy roots, while adults generally attack vines and leaves. They also spread foot rot, which creates enlarging brown to black areas on stems near the soil and at stem ends. Since weevils multiply quickly and are hard to eliminate, use certified disease-resistant slips and practice a 4-year crop rotation. Destroy infected plants and their roots, or place in sealed containers and dispose of them with household trash.
Fungal diseases include black rot, which results in circular, dark depressions on tubers. Discard infected potatoes, and cure the undamaged roots from the same crop carefully. Don't confuse this disease with less-serious scurf, which creates small, round, dark spots on tuber surfaces but doesn't affect eating quality. Stem rot, or wilt, is a fungus that enters plants injured by insects, careless cultivation, or wind. Even if this disease doesn't kill the plants, the harvest will be poor. Minimize the chances of disease by planting only healthy slips; avoid black and stem rot by planting resistant cultivars. Reduce the incidence of dry rot, which mummifies stored potatoes, by keeping the fleshy roots at 55° to 60°F.
You can harvest as soon as leaves start to yellow, but the longer a crop is left in the ground, the higher the yield and vitamin content. Once frost blackens the vines, however, tubers can quickly rot.
Use a spading fork to dig tubers on a sunny day when the soil is dry. Remember that tubers can grow a foot or more from the plant, and that any nicks on their tender skins will encourage spoilage. Dry tubers in the sun for several hours, then move them to a well-ventilated spot and keep at 85° to 90°F for 10 to 15 days. After they are cured, store at around 55ºF, with a humidity of 75 to 80 percent. Properly cured and stored sweet potatoes will keep for several months.